Surfactant protein A in chronic extrinsic allergic alveolitis.
نویسندگان
چکیده
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منابع مشابه
Involvement of eicosanoids and surfactant protein D in extrinsic allergic alveolitis.
The pathophysiology of extrinsic allergic alveolitis (EAA) involves oxidative lung damage as well as interstitial and alveolar inflammation. Macrophages and mast cells are inflammatory components of EAA that produce both leukotrienes (LTs) and prostaglandin D2 (PGD2). In addition, PGD2 is also produced by the free-radical-catalysed peroxidation of arachidonic acid during oxidative stress. Urina...
متن کامل[Extrinsic allergic alveolitis].
Extrinsic allergic alveolitis (EAA) or hypersensitivity pneumonitis is an interstitial lung disease associated with repeated exposure to a wide range of inhaled organic dusts and related occupational allergens, especially bird and fungal proteins. We focus on the diagnostic and prognostic findings related to the use of BAL in the management of EAA patients. The presentation of EAA varies from p...
متن کاملManganese superoxide dismutase, but not CuZn superoxide dismutase, is highly expressed in the granulomas of pulmonary sarcoidosis and extrinsic allergic alveolitis.
The role of antioxidant defense mechanisms in the pathogenesis of granulomatous human lung diseases remains open to investigation. In this study we investigated the immunoreactivity of two important superoxide radical scavenging intracellular antioxidant enzymes, manganese superoxide dismutase (MnSOD) and copperzinc superoxide dismutase (CuZnSOD), in pulmonary sarcoidosis and extrinsic allergic...
متن کاملRelationship between plasma cell levels and profile of bronchoalveolar lavage fluid in patients with subacute extrinsic allergic alveolitis.
BACKGROUND Plasma cells are usually absent in bronchoalveolar lavage (BAL) fluid. Extrinsic allergic alveolitis is associated with increased numbers of T and B lymphocytes in BAL fluid, as well as the presence of a few plasma cells. The aim of this study was to investigate whether there is a relationship between the presence of plasma cells and other cells, and immunoglobulin levels in BAL flui...
متن کاملTransfer of 99mTc DTPA and bronchoalveolar lavage findings in patients with asymptomatic extrinsic allergic alveolitis.
An investigation was performed to determine whether symptom free patients with previously diagnosed extrinsic allergic alveolitis had signs of inflammation in the lung. Pulmonary clearance of inhaled technetium-99m labelled diethylene triamine penta-acetic acid (DTPA) was measured in seven patients with a history of extrinsic allergic alveolitis but with no symptoms at the time of the study and...
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ورودعنوان ژورنال:
- The European respiratory journal
دوره 39 6 شماره
صفحات -
تاریخ انتشار 2012